Diagnostic Test
CNB (Core Needle Biopsy)
Description
Core Needle Biopsy (CNB) obtains cylinders of breast tissue for definitive histological study using an automatic spring-loaded needle. It is the reference standard for histological diagnosis of suspicious solid lesions. It is performed under local anaesthesia and real-time ultrasound guidance. It provides a complete histological diagnosis (type, grade and hormonal receptors in malignant lesions) essential for treatment planning.
Practical Information
15-30 minutes
Light breakfast on the day of the test. Do not apply deodorant or talcum powder. Inform us if you take aspirin, anti-inflammatory drugs, vitamin E, anticoagulants or antiplatelet drugs. Check with your doctor first: do not stop anticoagulants or antiplatelet drugs on your own — this must be indicated by the professional who prescribed them.
Price according to health insurance / private patient
Indications and Recommendations
- BI-RADS 4 and 5 lesions on mammography or ultrasound
- Suspicious solid nodules of malignancy
- Histological confirmation before surgery
- Complete characterisation of tumour receptors
Risks and Complications
- Bruising at the biopsy site
- Local pain or discomfort
- Bleeding, rarely significant
- Infection (uncommon)
- Vasovagal reaction (dizziness) during or after the procedure
- Insufficient sample requiring the biopsy to be repeated
- Higher bleeding risk in patients on anticoagulant or antiplatelet treatment
Frequently Asked Questions
Is core needle biopsy of the breast painful?
CNB is performed under local anaesthesia, so the patient only feels the initial anaesthesia injection. The procedure itself is practically painless. A slight discomfort may persist for 24-48 hours, similar to a small bruise.
How long does a CNB result take?
The histological result of CNB is usually available within 5-7 working days. In cases of clinical urgency, this can be expedited. The report includes a complete histological diagnosis and, if necessary, hormonal receptor study.
When is CNB indicated instead of FNAB?
CNB is indicated when a definitive histological diagnosis is needed, especially for BI-RADS 4 or 5 lesions. FNAB provides cytological diagnosis (less information), while CNB obtains complete tissue architecture, essential for planning surgery and oncological treatments.
What is the clip placed during CNB?
During CNB a small metal clip is placed in the lesion. This marker is inert and painless and serves so the surgeon can locate exactly the biopsied area in case of subsequent surgery. It does not need to be removed unless surgically indicated.